Across TCGA cell cohorts, H2AC18 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,343 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible H2AC18-associated GO terms across cancer lineages are Negative regulation of autophagy, Regulation of proteasomal protein catabolic process, and Regulation of protein sumoylation. Each is linked with H2AC18 in more than 13 cancer types. Because this analysis shows association rather than direction, both H2AC18-to-partner and partner-to-H2AC18 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AC18→partner) and Y-score (partner→H2AC18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Negative regulation of autophagy →	+0.087	+2.718	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of proteasomal protein catabolic process →	+0.073	+3.073	<.001	<.001	3	12
SKIN	Regulation of protein sumoylation →	+0.080	+1.433	.005	.006	3	12
OVARY	Vacuole organization →	+0.049	+1.997	<.001	.003	2	12
UPPER_AERODIGESTIVE_TRACT	Regulation of macroautophagy →	+0.055	+2.054	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Viral gene expression →	+0.097	+2.058	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,343 associations by consensus.

Exploration

H2AC18 survival (RNA) · tumor vs normal (RNA) · all H2AC18 data types