H2AC17

Across TCGA cell cohorts, H2AC17 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,136 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible H2AC17-associated GO terms across cancer lineages are Positive regulation of cell cycle phase transition, Cell cycle phase transition, and Regulation of DNA-templated DNA replication. Each is linked with H2AC17 in more than 10 cancer types. Because this analysis shows association rather than direction, both H2AC17-to-partner and partner-to-H2AC17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of cell cycle phase transition grouped by H2AC17-low versus H2AC17-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AC17→partner) and Y-score (partner→H2AC17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of cell cycle phase transition →	+0.067	+0.761	<.001	<.001	3	11
BLOOD_Leukemia	Cell cycle phase transition →	+0.053	+0.948	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of DNA-templated DNA replication →	+0.086	+0.761	.006	.005	3	10
SOFT_TISSUE	Mitotic chromosome condensation →	+0.126	+0.910	<.001	<.001	3	10
PANCREAS	Regulation of double-strand break repair via homologous recombination →	+0.059	+0.719	.003	.004	3	9
PANCREAS	Cell cycle DNA replication initiation →	+0.148	+0.701	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,136 associations by consensus.

Positive regulation of cell cycle phase transition by H2AC17 expression — PANCREAS

Explore this box plot interactively →