H2AC17

Across TCGA pan-cancer cohorts, H2AC17 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated H2AC17 data layer compared with 3 for mutation status.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher H2AC17 RNA is associated with better overall survival. In most high-consensus cancer types, elevated H2AC17 expression acts as an unfavorable survival marker, although some lineages such as OV and THYM show a favorable association.

OV, ESCA, and KIRC are the cancer types where H2AC17 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Median	All	0.898	0.780	<.001	120	view →
ESCA	DFS	Tertile	All	0.197	0.410	<.001	80	view →
KIRC	OS	Quartile	II,III,IV	0.728	0.914	<.001	72	view →
HNSC	OS	Quartile	All	0.693	0.838	.001	72	view →
ACC	DFS	Quartile	All	0.308	0.803	<.001	72	view →
PAAD	OS	Median	All	0.327	0.654	<.001	49	view →
LGG	OS	Median	All	0.376	0.521	<.001	39	view →
READ	DFS	Quartile	II,III,IV	0.609	0.984	.007	20	view →
CHOL	DFS	Median	II,III,IV	0.112	0.575	.023	19	view →
THYM	OS	Tertile	II,III,IV	1.000	0.506	.002	18	view →
SCLC	OS	Quartile	II,III,IV	0.609	0.213	.005	18	view →
KIRP	DFS	Quartile	All	0.582	0.903	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

H2AC17–OV (OS)

Open the OV breakdown →