H2AC12

Across TCGA pan-cancer cohorts, H2AC12 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated H2AC12 data layer compared with 26 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher H2AC12 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated H2AC12 expression acts as an unfavorable survival marker.

BLCA and COAD are the cancer types where H2AC12 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Median	All	0.174	0.625	.023	12	view →
COAD	DFS	Median	All	0.185	0.688	.030	3	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

H2AC12–BLCA (DFS)

Open the BLCA breakdown →