H2AB3

Across TCGA cell cohorts, H2AB3 protein abundance is significantly associated with the go_rna of many other GO terms, with 116 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible H2AB3-associated GO terms across cancer lineages are Negative regulation of lamellipodium assembly, Chromosomal DNA methylation maintenance following DNA replication, and C4-dicarboxylate transport. Each is linked with H2AB3 in more than 1 cancer types. Because this analysis shows association rather than direction, both H2AB3-to-partner and partner-to-H2AB3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of lamellipodium assembly grouped by H2AB3-low versus H2AB3-high in BLOOD_Lymphoma.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AB3→partner) and Y-score (partner→H2AB3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Negative regulation of lamellipodium assembly →	+0.376	+2.381	.001	.005	3	1
BLOOD_Lymphoma	Chromosomal DNA methylation maintenance following DNA replication →	-0.093	-2.454	.007	.002	3	1
BLOOD_Lymphoma	C4-dicarboxylate transport →	+0.227	+2.381	.002	.005	3	1
BLOOD_Lymphoma	tRNA 5'-leader removal →	+0.169	+2.381	.008	.005	3	1
BLOOD_Lymphoma	Positive regulation of purine nucleotide biosynthetic process →	+0.154	+2.381	<.001	.005	3	1
BLOOD_Lymphoma	Regulation of lung ciliated cell differentiation →	+1.905	+2.381	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 116 associations by consensus.

Negative regulation of lamellipodium assembly by H2AB3 expression — BLOOD_Lymphoma

Explore this box plot interactively →