H1-8

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, H1-8 RNA expression is significantly associated with the protein abundance of many other proteins, with 5,045 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible H1-8-associated proteins across cancer lineages are RCN3, ZDHHC5_S274, and AEBP1. Each is linked with H1-8 in more than 2 cancer types. Because this analysis shows association rather than direction, both H1-8-to-partner and partner-to-H1-8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H1-8 versus RCN3 in GBM, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H1-8→partner) and Y-score (partner→H1-8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMRCN3 →+0.564+0.141<.001<.00133
PDACZDHHC5_S274 →-0.684-0.068<.001.00733
CCRCCAEBP1 →+0.565+0.114<.001<.00133
GBMCOL15A1 →+0.546+0.181.001<.00133
CCRCCECM2_S213 →+0.944+0.162<.001<.00133
CCRCCPRKAB2_S158 →-0.984-0.218<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,045 associations by consensus.

H1-8 vs RCN3 — GBM

Per-sample scatter of H1-8 vs RCN3 in GBM (Pearson r = 0.45).

Explore this scatter interactively →

Exploration