Across TCGA patient cohorts, H1-6 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,060 significant associations in total. GBM shows the largest number of these associations.

The most reproducible H1-6-associated proteins across cancer lineages are UBE2S, TTC7A_S647, and NCL_T76. Each is linked with H1-6 in more than 3 cancer types. Because this analysis shows association rather than direction, both H1-6-to-partner and partner-to-H1-6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H1-6→partner) and Y-score (partner→H1-6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	UBE2S →	+0.490	+0.651	<.001	<.001	3	4
GBM	TTC7A_S647 →	-0.475	-0.709	.004	<.001	3	3
LUAD	NCL_T76 →	+1.327	+0.719	<.001	.002	3	3
LUAD	NCL_T84 →	+1.005	+0.666	.004	.009	3	3
LSCC	OCIAD1_S108 →	+1.238	+0.825	<.001	<.001	3	3
HNSC	CDCA5 →	+0.627	+0.979	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,060 associations by consensus.

Exploration

H1-6 survival (RNA) · tumor vs normal (RNA) · all H1-6 data types