Across TCGA patient cohorts, H1-6 protein abundance is significantly associated with the RNA expression of many other genes, with 284 significant associations in total. OV shows the largest number of these associations.

The most reproducible H1-6-associated genes across cancer lineages are RSPH14, ZNF174, and CLUAP1. Each is linked with H1-6 in more than 1 cancer types. Because this analysis shows association rather than direction, both H1-6-to-partner and partner-to-H1-6 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H1-6→partner) and Y-score (partner→H1-6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RSPH14 →	+0.455	+1.040	.002	.003	3	1
OV	ZNF174 →	+0.686	+0.882	.002	.008	3	1
OV	CLUAP1 →	+0.762	+0.885	.001	.005	3	1
OV	KAT8 →	+0.475	+0.725	.009	.003	3	1
OV	SLC25A11 →	+0.629	+1.156	<.001	.002	3	1
OV	MED31 →	+0.518	+0.691	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 284 associations by consensus.

Exploration

H1-6 survival (RNA) · tumor vs normal (RNA) · all H1-6 data types