Across TCGA cell cohorts, H1-6 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,110 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible H1-6-associated GO terms across cancer lineages are Process utilizing autophagic mechanism, Autophagy, and Protein localization to CENP-A containing chromatin. Each is linked with H1-6 in more than 6 cancer types. Because this analysis shows association rather than direction, both H1-6-to-partner and partner-to-H1-6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H1-6→partner) and Y-score (partner→H1-6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Process utilizing autophagic mechanism →	+0.044	+0.192	<.001	.001	3	7
OVARY	Autophagy →	+0.044	+0.192	<.001	.001	3	7
LUNG_SCLC	Protein localization to CENP-A containing chromatin →	+0.276	+0.301	<.001	<.001	3	7
OVARY	Regulation of mRNA splicing, via spliceosome →	+0.050	+0.122	<.001	.005	3	7
OVARY	Cellular response to nutrient levels →	+0.036	+0.130	.002	.005	2	7
LUNG_NSCLC_LUAD	Vacuole organization →	+0.026	+0.131	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,110 associations by consensus.

Exploration

H1-6 survival (RNA) · tumor vs normal (RNA) · all H1-6 data types