H1-5

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, H1-5 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,954 significant associations in total. GBM shows the largest number of these associations.

The most reproducible H1-5-associated proteins across cancer lineages are NCAPD2, SMC2, and SMC4. Each is linked with H1-5 in more than 7 cancer types. Because this analysis shows association rather than direction, both H1-5-to-partner and partner-to-H1-5 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H1-5→partner) and Y-score (partner→H1-5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMNCAPD2 →+0.791+1.713<.001<.00138
GBMSMC2 →+0.807+1.702<.001<.00138
GBMSMC4 →+0.794+1.681<.001<.00138
LUADMCM2_S27 →+0.982+1.400<.001<.00138
BRCACDK1 →+0.839+0.458<.001<.00138
OVHAT1 →+0.462+0.474.001.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 19,954 associations by consensus.

Exploration