H1-4

Across TCGA patient cohorts, H1-4 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,545 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible H1-4-associated proteins across cancer lineages are CDYL_S216, RBBP5_S497, and RFC2. Each is linked with H1-4 in more than 6 cancer types. Because this analysis shows association rather than direction, both H1-4-to-partner and partner-to-H1-4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H1-4 versus CDYL_S216 in LUAD, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H1-4→partner) and Y-score (partner→H1-4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CDYL_S216 →	+0.686	+0.379	<.001	<.001	3	7
GBM	RBBP5_S497 →	+0.837	+0.730	<.001	<.001	3	6
GBM	RFC2 →	+0.464	+0.824	<.001	<.001	3	6
LUAD	RMDN2 →	-0.453	-0.445	<.001	<.001	3	6
GBM	DNMT1 →	+0.445	+0.729	<.001	<.001	3	6
UCEC	MAD2L1 →	+0.692	+1.885	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,545 associations by consensus.

H1-4 vs CDYL_S216 — LUAD

Explore this scatter interactively →