Across TCGA patient cohorts, H1-10 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. COAD shows the largest number of these associations.

The most reproducible H1-10-associated genes across cancer lineages are LINC01708, SNRPCP15, and MTCO3P10. Each is linked with H1-10 in more than 1 cancer types. Because this analysis shows association rather than direction, both H1-10-to-partner and partner-to-H1-10 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H1-10→partner) and Y-score (partner→H1-10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LINC01708 →	+0.122	+5.003	<.001	.004	3	1
COAD	SNRPCP15 →	+0.244	+5.392	<.001	.002	3	1
COAD	MTCO3P10 →	+0.169	+5.321	.003	.001	3	1
COAD	CTBP2P1 →	+0.276	+5.721	.001	.001	3	1
COAD	LINC01072 →	+0.111	+4.516	<.001	.009	3	1
COAD	LINC02702 →	+0.300	+4.354	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

H1-10 survival (RNA) · tumor vs normal (RNA) · all H1-10 data types