Across TCGA cell cohorts, H1-10 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,144 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible H1-10-associated GO terms across cancer lineages are Positive regulation of proteasomal ubiquitin-dependent protein catabolic process, Positive regulation of proteasomal protein catabolic process, and Positive regulation of intracellular steroid hormone receptor signaling pathway. Each is linked with H1-10 in more than 14 cancer types. Because this analysis shows association rather than direction, both H1-10-to-partner and partner-to-H1-10 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H1-10→partner) and Y-score (partner→H1-10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.063	+0.834	<.001	.003	3	15
OVARY	Positive regulation of proteasomal protein catabolic process →	+0.065	+0.858	.001	<.001	3	13
OVARY	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.128	+0.955	.002	.002	3	12
BONE	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.178	+1.238	.001	.002	3	12
BONE	Negative regulation of syncytium formation by plasma membrane fusion →	+0.122	+1.658	<.001	<.001	3	12
OESOPHAGUS	Mitochondrial electron transport, cytochrome c to oxygen →	+0.141	+1.187	.008	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,144 associations by consensus.

Exploration

H1-10 survival (RNA) · tumor vs normal (RNA) · all H1-10 data types