GZMM

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GZMM mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GZMM-associated genes across cancer lineages are Adipocytes and Eosinophils. Each is linked with GZMM in more than 1 cancer types. Because this analysis shows association rather than direction, both GZMM-to-partner and partner-to-GZMM results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GZMM→partner) and Y-score (partner→GZMM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECAdipocytes →+0.035+2.144<.001.03631
UCECEosinophils →+0.069+2.202.015.03421
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration