Across TCGA cell cohorts, GZMM RNA expression is significantly associated with the go_rna of many other GO terms, with 3,368 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GZMM-associated GO terms across cancer lineages are Regulation of syncytium formation by plasma membrane fusion, RNA catabolic process, and Cytoplasmic translation. Each is linked with GZMM in more than 8 cancer types. Because this analysis shows association rather than direction, both GZMM-to-partner and partner-to-GZMM results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GZMM→partner) and Y-score (partner→GZMM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Regulation of syncytium formation by plasma membrane fusion →	+0.073	+0.299	<.001	.004	3	9
BONE	RNA catabolic process →	+0.054	+1.371	<.001	<.001	3	9
LARGE_INTESTINE	Cytoplasmic translation →	+0.065	+0.293	<.001	.003	3	8
BONE	Subtelomeric heterochromatin formation →	+0.120	+1.415	.001	.001	3	8
BONE	Nucleic acid catabolic process →	+0.046	+1.467	<.001	<.001	3	7
UPPER_AERODIGESTIVE_TRACT	Positive regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.081	+0.247	.001	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,368 associations by consensus.

Exploration

GZMM survival (RNA) · tumor vs normal (RNA) · all GZMM data types