GZMH

Across TCGA patient cohorts, GZMH RNA expression is significantly associated with the protein abundance of many other proteins, with 13,488 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GZMH-associated proteins across cancer lineages are RCSD1, ITGAL, and LCP1. Each is linked with GZMH in more than 9 cancer types. Because this analysis shows association rather than direction, both GZMH-to-partner and partner-to-GZMH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GZMH versus RCSD1 in OV, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GZMH→partner) and Y-score (partner→GZMH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RCSD1 →	+0.577	+1.334	<.001	<.001	3	10
CCRCC	ITGAL →	+0.686	+1.160	<.001	<.001	3	10
GBM	LCP1 →	+0.739	+1.068	<.001	<.001	3	10
HNSC	LCP2 →	+0.650	+1.578	<.001	<.001	3	10
BRCA	APOL3 →	+0.775	+1.429	<.001	<.001	3	10
COAD	NFATC2 →	+0.804	+1.079	<.001	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,488 associations by consensus.

GZMH vs RCSD1 — OV

Explore this scatter interactively →