GZMH

Across TCGA cell cohorts, GZMH RNA expression is significantly associated with the go_rna of many other GO terms, with 605 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GZMH-associated GO terms across cancer lineages are Oxygen transport, Negative regulation of phospholipid metabolic process, and Lateral mesoderm development. Each is linked with GZMH in more than 2 cancer types. Because this analysis shows association rather than direction, both GZMH-to-partner and partner-to-GZMH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Oxygen transport grouped by GZMH-low versus GZMH-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GZMH→partner) and Y-score (partner→GZMH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Oxygen transport →	+0.856	+0.035	.009	.006	3	3
BLOOD_Myeloma	Negative regulation of phospholipid metabolic process →	+0.257	+0.101	<.001	.005	3	2
BLOOD_Myeloma	Lateral mesoderm development →	+0.158	+0.079	.002	.009	3	2
BLOOD_Myeloma	Energy homeostasis →	-0.057	-0.086	.002	.006	3	2
LUNG_SCLC	Pyrimidine nucleobase biosynthetic process →	+0.092	+0.053	.003	.006	3	2
LUNG_SCLC	B cell receptor signaling pathway →	-0.065	-0.043	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 605 associations by consensus.

Oxygen transport by GZMH expression — LUNG_SCLC

Explore this box plot interactively →