GYPA

Across TCGA patient cohorts, GYPA protein abundance is significantly associated with the RNA expression of many other genes, with 2,830 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible GYPA-associated genes across cancer lineages are HBB, HBA2, and HBA1. Each is linked with GYPA in more than 8 cancer types. Because this analysis shows association rather than direction, both GYPA-to-partner and partner-to-GYPA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GYPA versus HBB in PDAC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GYPA→partner) and Y-score (partner→GYPA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	HBB →	+2.926	+0.788	<.001	.001	3	9
PDAC	HBA2 →	+2.540	+0.797	<.001	.001	3	8
GBM	HBA1 →	+1.576	+0.982	<.001	<.001	3	8
OV	DUSP1 →	+1.551	+1.067	<.001	<.001	3	5
GBM	PF4 →	+0.951	+0.749	<.001	<.001	3	5
OV	ZFP36 →	+1.139	+0.717	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,830 associations by consensus.

GYPA vs HBB — PDAC

Explore this scatter interactively →