GXYLT1P4

Across TCGA pan-cancer cohorts, GXYLT1P4 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated GXYLT1P4 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher GXYLT1P4 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated GXYLT1P4 expression acts as an unfavorable survival marker, although some lineages such as BRCA and GBM show a favorable association.

UCEC, UCS, and KICH are the cancer types where GXYLT1P4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	All	0.506	0.661	.018	78	view →
UCS	DFS	Tertile	IV	0.230	0.767	.009	36	view →
KICH	DFS	Quartile	II,III,IV	0.083	0.928	<.001	30	view →
MESO	DFS	Tertile	II,III,IV	0.113	0.542	.001	27	view →
BRCA	DFS	Tertile	III,IV	0.908	0.756	.008	26	view →
THCA	OS	Quartile	II,III,IV	0.597	0.924	<.001	24	view →
LGG	DFS	Quartile	All	0.598	0.848	.003	21	view →
GBM	DFS	Median	All	0.400	0.195	.004	19	view →
STAD	DFS	Quartile	All	0.388	0.588	.011	18	view →
CESC	OS	Quartile	All	0.940	0.759	.005	12	view →
LUAD	DFS	Tertile	IV	0.862	0.358	.030	12	view →
HNSC	DFS	Tertile	IV	0.760	0.616	.027	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

GXYLT1P4–UCEC (DFS)

Open the UCEC breakdown →