GXYLT1P4

Across TCGA pan-cancer cohorts, GXYLT1P4 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of GXYLT1P4’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where GXYLT1P4 RNA is repressed in tumor relative to normal tissue. In most cancer types GXYLT1P4 is over-expressed in tumor, although a few such as COAD and THCA show the opposite, repressed pattern.

COAD, THCA, and BRCA are the cancer types where GXYLT1P4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GXYLT1P4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	−0.023	<.001	8	view →
THCA	All	All	−0.037	<.001	7	view →
BRCA	All	All	−0.085	<.001	6	view →
LUAD	Female	All	−0.046	.005	4	view →
PAAD	All	All	−0.057	.009	2	view →
READ	All	All	−0.032	.018	2	view →
LIHC	Female	All	−0.024	.009	2	view →
LUSC	Female	II,III,IV	−0.075	.004	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

GXYLT1P4–COAD

Open the COAD breakdown →