GVINP1

Across TCGA patient cohorts, GVINP1 mutation is significantly associated with the RNA expression of many other genes, with 5,092 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GVINP1-associated genes across cancer lineages are RNU6-628P, C3orf38, and RAD23A. Each is linked with GVINP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GVINP1-to-partner and partner-to-GVINP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-628P grouped by GVINP1-low versus GVINP1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GVINP1→partner) and Y-score (partner→GVINP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU6-628P →	+0.350	+2.914	<.001	.003	3	2
UCEC	C3orf38 →	+0.371	+2.321	.002	.001	3	2
UCEC	RAD23A →	+0.368	+1.828	.003	<.001	3	2
UCEC	PRKRA →	+0.430	+3.119	<.001	<.001	3	2
UCEC	IBA57 →	+0.281	+3.016	.006	<.001	3	2
UCEC	MRPS16 →	+0.382	+2.082	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,092 associations by consensus.

RNU6-628P by GVINP1 expression — CESC

Explore this box plot interactively →