GUSBP7

Across TCGA patient cohorts, GUSBP7 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,836 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GUSBP7-associated GO terms across cancer lineages are Regulation of double-strand break repair via nonhomologous end joining, Regulation of telomerase activity, and Regulation of double-strand break repair via homologous recombination. Each is linked with GUSBP7 in more than 15 cancer types. Because this analysis shows association rather than direction, both GUSBP7-to-partner and partner-to-GUSBP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of double-strand break repair via nonhomologous end joining grouped by GUSBP7-low versus GUSBP7-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GUSBP7→partner) and Y-score (partner→GUSBP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of double-strand break repair via nonhomologous end joining →	+0.059	+0.292	<.001	.001	3	16
STAD	Regulation of telomerase activity →	+0.062	+0.170	<.001	<.001	3	16
STAD	Regulation of double-strand break repair via homologous recombination →	+0.064	+0.166	<.001	<.001	3	14
STAD	Peptidyl-lysine acetylation →	+0.067	+0.203	<.001	<.001	3	14
ESCA	tRNA modification →	+0.058	+0.224	<.001	.009	1	16
STAD	Protein targeting to mitochondrion →	+0.057	+0.139	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,836 associations by consensus.

Regulation of double-strand break repair via nonhomologous end joining by GUSBP7 expression — ESCA

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