GUSBP7

Across TCGA pan-cancer cohorts, GUSBP7 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated GUSBP7 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher GUSBP7 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated GUSBP7 expression acts as an unfavorable survival marker, although some lineages such as UCS and LGG show a favorable association.

MESO, THCA, and UCS are the cancer types where GUSBP7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Tertile	All	0.128	0.512	.002	90	view →
THCA	OS	Tertile	IV	0.446	0.892	<.001	60	view →
UCS	OS	Median	II,III,IV	0.663	0.350	.016	40	view →
CESC	OS	Tertile	All	0.723	0.885	.001	36	view →
LGG	DFS	Median	All	0.800	0.675	<.001	36	view →
GBM	OS	Tertile	All	0.272	0.486	<.001	18	view →
READ	OS	Tertile	III,IV	0.555	0.888	.020	18	view →
DLBC	OS	Tertile	III,IV	0.272	1.000	.017	16	view →
COAD	DFS	Tertile	All	0.322	0.544	.018	12	view →
UCEC	DFS	Tertile	IV	0.966	0.588	.027	12	view →
UVM	DFS	Tertile	III,IV	0.079	0.635	.021	9	view →
PAAD	DFS	Tertile	All	0.781	0.322	.021	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

GUSBP7–MESO (DFS)

Open the MESO breakdown →