GUSBP3

Across TCGA patient cohorts, GUSBP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,953 significant associations in total. THCA shows the largest number of these associations.

The most reproducible GUSBP3-associated GO terms across cancer lineages are Regulation of centriole replication, Epigenetic regulation of gene expression, and Centrosome duplication. Each is linked with GUSBP3 in more than 16 cancer types. Because this analysis shows association rather than direction, both GUSBP3-to-partner and partner-to-GUSBP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of centriole replication grouped by GUSBP3-low versus GUSBP3-high in LAML.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GUSBP3→partner) and Y-score (partner→GUSBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Regulation of centriole replication →	+0.048	+0.321	<.001	<.001	3	17
THYM	Epigenetic regulation of gene expression →	+0.038	+0.500	<.001	<.001	3	16
THYM	Centrosome duplication →	+0.056	+0.619	<.001	<.001	2	17
THYM	Centriole assembly →	+0.067	+0.577	<.001	<.001	3	16
THYM	snRNA metabolic process →	+0.039	+0.439	<.001	<.001	2	16
THYM	Microtubule organizing center organization →	+0.044	+0.491	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,953 associations by consensus.

Regulation of centriole replication by GUSBP3 expression — LAML

Explore this box plot interactively →