GULOP

Across TCGA pan-cancer cohorts, GULOP RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated GULOP data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher GULOP RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated GULOP expression acts as an unfavorable survival marker, although some lineages such as KIRC and SKCM show a favorable association.

UCEC, KIRC, and THCA are the cancer types where GULOP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Quartile	III,IV	0.640	0.834	<.001	80	view →
KIRC	OS	Tertile	All	0.927	0.826	<.001	42	view →
THCA	DFS	Quartile	All	0.760	0.926	.015	38	view →
DLBC	DFS	Tertile	IV	0.120	0.683	.001	36	view →
ESCA	OS	Quartile	II,III,IV	0.354	0.614	.004	33	view →
SKCM	DFS	Tertile	All	0.299	0.168	.002	24	view →
UCS	DFS	Tertile	II,III,IV	0.631	0.197	.012	22	view →
UVM	OS	Quartile	II,III,IV	0.947	0.477	.004	19	view →
ACC	OS	Tertile	II,III,IV	0.769	0.272	.007	16	view →
KIRP	DFS	Median	All	0.473	0.702	.001	13	view →
PCPG	DFS	Tertile	All	0.955	0.818	.017	13	view →
READ	DFS	Median	All	0.354	0.765	.012	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

GULOP–UCEC (DFS)

Open the UCEC breakdown →