GUK1

Across TCGA patient cohorts, GUK1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,311 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible GUK1-associated proteins across cancer lineages are RNPEP, BAIAP2L1, and FBL. Each is linked with GUK1 in more than 3 cancer types. Because this analysis shows association rather than direction, both GUK1-to-partner and partner-to-GUK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GUK1 versus RNPEP in LSCC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GUK1→partner) and Y-score (partner→GUK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RNPEP →	+0.276	+0.348	<.001	<.001	3	4
LUAD	BAIAP2L1 →	+0.500	+0.466	.001	<.001	3	4
COAD	FBL →	-0.329	-0.637	<.001	<.001	3	4
PDAC	GNPAT →	+0.305	+0.300	.006	<.001	3	4
LSCC	YY1 →	-0.270	-0.359	<.001	.001	3	3
CCRCC	ARID3A →	-0.512	-0.427	.007	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,311 associations by consensus.

GUK1 vs RNPEP — LSCC

Explore this scatter interactively →