GUK1

Across TCGA patient cohorts, GUK1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,231 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GUK1-associated genes across cancer lineages are WRAP53, SCN3B, and CEP76. Each is linked with GUK1 in more than 3 cancer types. Because this analysis shows association rather than direction, both GUK1-to-partner and partner-to-GUK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GUK1 versus WRAP53 in LSCC, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GUK1→partner) and Y-score (partner→GUK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	WRAP53 →	-0.527	-0.165	<.001	.001	3	4
GBM	SCN3B →	+1.172	+0.292	<.001	<.001	3	3
LSCC	CEP76 →	-0.533	-0.170	<.001	.007	3	3
GBM	CAB39L →	+0.597	+0.219	.001	<.001	3	3
GBM	DSTYK →	+0.337	+0.320	<.001	<.001	3	3
HNSC	LINC02777 →	+0.548	+0.239	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,231 associations by consensus.

GUK1 vs WRAP53 — LSCC

Explore this scatter interactively →