GUCY2D

Across TCGA patient cohorts, GUCY2D RNA expression is significantly associated with the go_rna of many other GO terms, with 7,150 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GUCY2D-associated GO terms across cancer lineages are Rhodopsin mediated signaling pathway, Phototransduction, visible light, and Lipoxin metabolic process. Each is linked with GUCY2D in more than 21 cancer types. Because this analysis shows association rather than direction, both GUCY2D-to-partner and partner-to-GUCY2D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Rhodopsin mediated signaling pathway grouped by GUCY2D-low versus GUCY2D-high in LIHC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GUCY2D→partner) and Y-score (partner→GUCY2D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	Rhodopsin mediated signaling pathway →	-0.074	-0.418	<.001	<.001	3	22
CHOL	Phototransduction, visible light →	-0.073	-0.692	.004	.002	1	19
DLBC	Lipoxin metabolic process →	+0.090	+0.222	<.001	.003	2	17
STAD	Regulation of endosome size →	+0.044	+0.153	<.001	<.001	3	16
STAD	Regulation of lysosome size →	+0.035	+0.143	<.001	<.001	3	16
STAD	Proton motive force-driven ATP synthesis →	+0.052	+0.125	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,150 associations by consensus.

Rhodopsin mediated signaling pathway by GUCY2D expression — LIHC

Explore this box plot interactively →