GUCY1B1

Across TCGA cell cohorts, GUCY1B1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,848 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GUCY1B1-associated GO terms across cancer lineages are Regulation of myoblast fusion, Negative regulation of mitotic cell cycle phase transition, and COPI-coated vesicle budding. Each is linked with GUCY1B1 in more than 8 cancer types. Because this analysis shows association rather than direction, both GUCY1B1-to-partner and partner-to-GUCY1B1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by GUCY1B1-low versus GUCY1B1-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GUCY1B1→partner) and Y-score (partner→GUCY1B1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of myoblast fusion →	+0.098	+1.396	.002	.005	3	8
BREAST	Negative regulation of mitotic cell cycle phase transition →	+0.057	+1.318	.003	.005	3	8
SOFT_TISSUE	COPI-coated vesicle budding →	+0.110	+1.310	<.001	.001	3	8
SOFT_TISSUE	Golgi transport vesicle coating →	+0.110	+1.310	<.001	.001	3	8
SOFT_TISSUE	COPI coating of Golgi vesicle →	+0.110	+1.310	<.001	.001	3	8
SOFT_TISSUE	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.068	+1.322	.001	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,848 associations by consensus.

Regulation of myoblast fusion by GUCY1B1 expression — PANCREAS

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