GUCD1

Across TCGA patient cohorts, GUCD1 mutation is significantly associated with the RNA expression of many other genes, with 202 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GUCD1-associated genes across cancer lineages are CDRT15P7, MAP3K4-AS1, and RNA5SP414. Each is linked with GUCD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GUCD1-to-partner and partner-to-GUCD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CDRT15P7 grouped by GUCD1-low versus GUCD1-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GUCD1→partner) and Y-score (partner→GUCD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CDRT15P7 →	+0.068	+5.122	.002	.008	3	1
UCEC	MAP3K4-AS1 →	+0.818	+3.191	.001	.009	3	1
UCEC	RNA5SP414 →	+0.771	+2.577	<.001	.004	3	1
UCEC	RNA5SP412 →	+0.727	+2.744	<.001	.001	3	1
UCEC	RNVU1-28 →	+0.819	+3.372	<.001	<.001	3	1
UCEC	SENP3-EIF4A1 →	+0.126	+3.437	.003	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 202 associations by consensus.

CDRT15P7 by GUCD1 expression — BRCA

Explore this box plot interactively →