GUCA2B

Across TCGA patient cohorts, GUCA2B RNA expression is significantly associated with the go_rna of many other GO terms, with 5,973 significant associations in total. COAD shows the largest number of these associations.

The most reproducible GUCA2B-associated GO terms across cancer lineages are Primary alcohol metabolic process, Calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules, and Regulation of proton transport. Each is linked with GUCA2B in more than 10 cancer types. Because this analysis shows association rather than direction, both GUCA2B-to-partner and partner-to-GUCA2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Primary alcohol metabolic process grouped by GUCA2B-low versus GUCA2B-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GUCA2B→partner) and Y-score (partner→GUCA2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Primary alcohol metabolic process →	+0.028	+0.440	<.001	<.001	3	11
ESCA	Calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules →	+0.095	+0.699	<.001	<.001	3	10
ESCA	Regulation of proton transport →	+0.063	+0.629	<.001	<.001	3	10
PAAD	Olefinic compound metabolic process →	+0.016	+0.588	<.001	<.001	3	10
ESCA	Putrescine metabolic process →	+0.094	+0.608	<.001	<.001	3	9
ESCA	Epithelial structure maintenance →	+0.063	+0.610	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,973 associations by consensus.

Primary alcohol metabolic process by GUCA2B expression — STAD

Explore this box plot interactively →