Across TCGA patient cohorts, GUCA2A RNA expression is significantly associated with the go_rna of many other GO terms, with 6,602 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible GUCA2A-associated GO terms across cancer lineages are Regulation of proton transport, Respiratory electron transport chain, and Monocarboxylic acid catabolic process. Each is linked with GUCA2A in more than 9 cancer types. Because this analysis shows association rather than direction, both GUCA2A-to-partner and partner-to-GUCA2A results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GUCA2A→partner) and Y-score (partner→GUCA2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of proton transport →	+0.042	+1.242	<.001	<.001	3	10
DLBC	Respiratory electron transport chain →	+0.063	+0.071	.002	.002	2	10
ESCA	Monocarboxylic acid catabolic process →	+0.032	+0.978	<.001	<.001	3	9
ESCA	Nucleoside phosphate biosynthetic process →	+0.027	+1.078	<.001	<.001	3	9
TGCT	Negative regulation of Notch signaling pathway →	+0.053	+1.044	<.001	<.001	3	9
ESCA	Organic acid catabolic process →	+0.031	+1.075	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,602 associations by consensus.

Exploration

GUCA2A survival (RNA) · tumor vs normal (RNA) · all GUCA2A data types