GUCA1B

Across TCGA patient cohorts, GUCA1B RNA expression is significantly associated with the go_rna of many other GO terms, with 7,147 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible GUCA1B-associated GO terms across cancer lineages are Telomere organization, Macromolecule methylation, and Telomere maintenance. Each is linked with GUCA1B in more than 31 cancer types. Because this analysis shows association rather than direction, both GUCA1B-to-partner and partner-to-GUCA1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere organization grouped by GUCA1B-low versus GUCA1B-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GUCA1B→partner) and Y-score (partner→GUCA1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Telomere organization →	+0.080	+1.393	<.001	<.001	2	32
STAD	Macromolecule methylation →	+0.054	+0.331	<.001	<.001	3	31
SCLC	Telomere maintenance →	+0.084	+1.470	<.001	<.001	3	31
STAD	Obsolete regulation of dosage compensation by inactivation of X chromosome →	+0.075	+0.395	<.001	<.001	3	31
SCLC	Regulation of RNA splicing →	+0.072	+1.275	<.001	<.001	3	31
SCLC	Negative regulation of gene expression, epigenetic →	+0.167	+1.437	<.001	<.001	3	31

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,147 associations by consensus.

Telomere organization by GUCA1B expression — SCLC

Explore this box plot interactively →