GUCA1B

Across TCGA patient cohorts, GUCA1B mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GUCA1B-associated genes across cancer lineages are p62 Lck ligand and Ku80. Each is linked with GUCA1B in more than 1 cancer types. Because this analysis shows association rather than direction, both GUCA1B-to-partner and partner-to-GUCA1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p62 Lck ligand grouped by GUCA1B-low versus GUCA1B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GUCA1B→partner) and Y-score (partner→GUCA1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p62 Lck ligand →	+0.490	+2.817	.014	.036	3	1
UCEC	Ku80 →	+0.313	+2.820	.030	.036	1	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

p62 Lck ligand by GUCA1B expression — UCEC

Explore this box plot interactively →