GUCA1B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GUCA1B RNA expression is significantly associated with the go_rna of many other GO terms, with 2,916 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GUCA1B-associated GO terms across cancer lineages are Sperm-egg recognition, Otolith mineralization, and Regulation of autophagosome assembly. Each is linked with GUCA1B in more than 7 cancer types. Because this analysis shows association rather than direction, both GUCA1B-to-partner and partner-to-GUCA1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sperm-egg recognition grouped by GUCA1B-low versus GUCA1B-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GUCA1B→partner) and Y-score (partner→GUCA1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OESOPHAGUSSperm-egg recognition →-0.170-0.667<.001.00337
LARGE_INTESTINEOtolith mineralization →+0.093+0.780<.001.00628
UPPER_AERODIGESTIVE_TRACTRegulation of autophagosome assembly →+0.072+0.824.004.00137
BLOOD_LeukemiaProtein modification by small protein removal →+0.049+0.777<.001<.00137
KIDNEYmiRNA metabolic process →+0.064+0.778.001.00137
LUNG_NSCLC_LUADCilium or flagellum-dependent cell motility →-0.060-0.844<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,916 associations by consensus.

Sperm-egg recognition by GUCA1B expression — OESOPHAGUS

Box plot of Sperm-egg recognition in GUCA1B-low vs GUCA1B-high samples in OESOPHAGUS.

Explore this box plot interactively →

Exploration