GTPBP3

Across TCGA patient cohorts, GTPBP3 protein abundance is significantly associated with the RNA expression of many other genes, with 7,348 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GTPBP3-associated genes across cancer lineages are PDE1A, SLC35E1, and MYC. Each is linked with GTPBP3 in more than 3 cancer types. Because this analysis shows association rather than direction, both GTPBP3-to-partner and partner-to-GTPBP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GTPBP3 versus PDE1A in OV, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTPBP3→partner) and Y-score (partner→GTPBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PDE1A →	-0.977	-0.346	.002	.001	3	3
LSCC	SLC35E1 →	+0.382	+0.326	<.001	<.001	3	3
BRCA	MYC →	+1.122	+0.309	<.001	<.001	3	3
UCEC	SGCD →	-0.983	-0.305	.008	.006	3	3
HNSC	DOT1L →	+0.731	+0.448	<.001	<.001	3	3
HNSC	SF3A2 →	+0.682	+0.276	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,348 associations by consensus.

GTPBP3 vs PDE1A — OV

Explore this scatter interactively →