GTPBP3

Across TCGA cell cohorts, GTPBP3 mutation is significantly associated with the mutation status of many other genes, with 1,913 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GTPBP3-associated genes across cancer lineages are COLGALT1, RARA, and HCN4. Each is linked with GTPBP3 in more than 2 cancer types. Because this analysis shows association rather than direction, both GTPBP3-to-partner and partner-to-GTPBP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COLGALT1 grouped by GTPBP3-low versus GTPBP3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTPBP3→partner) and Y-score (partner→GTPBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	COLGALT1 →	+4.050	+3.870	.002	.002	1	3
BLOOD_Leukemia	RARA →	+2.880	+3.495	.002	.002	1	3
BLOOD_Leukemia	HCN4 →	+3.243	+3.762	.001	.001	1	3
BLOOD_Leukemia	ZCCHC14 →	+3.635	+3.635	.003	.003	1	3
BLOOD_Leukemia	ERBB2 →	+3.243	+3.762	.001	.001	1	3
BLOOD_Leukemia	FCSK →	+3.243	+3.762	.001	.001	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,913 associations by consensus.

COLGALT1 by GTPBP3 expression — BLOOD_Leukemia

Explore this box plot interactively →