GTF3C6

Across TCGA patient cohorts, GTF3C6 mutation is significantly associated with the RNA expression of many other genes, with 62 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GTF3C6-associated genes across cancer lineages are RNA5SP422, MIR3135A, and RN7SL627P. Each is linked with GTF3C6 in more than 1 cancer types. Because this analysis shows association rather than direction, both GTF3C6-to-partner and partner-to-GTF3C6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP422 grouped by GTF3C6-low versus GTF3C6-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF3C6→partner) and Y-score (partner→GTF3C6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNA5SP422 →	+0.308	+6.164	<.001	<.001	3	2
COAD	MIR3135A →	+0.882	+4.602	<.001	.008	3	2
CESC	RN7SL627P →	+0.168	+5.891	<.001	<.001	3	2
COAD	MIR4710 →	+0.713	+4.602	<.001	.008	3	2
UCEC	RPS27P20 →	+0.235	+3.185	.002	.001	3	2
UCEC	C1QTNF9-AS1 →	+0.113	+3.063	.007	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 62 associations by consensus.

RNA5SP422 by GTF3C6 expression — CESC

Explore this box plot interactively →