GTF3C2-AS1

Across TCGA pan-cancer cohorts, GTF3C2-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated GTF3C2-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher GTF3C2-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated GTF3C2-AS1 expression acts as an unfavorable survival marker, although some lineages such as READ and UCS show a favorable association.

KIRC, ACC, and READ are the cancer types where GTF3C2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.533	0.702	<.001	98	view →
ACC	OS	Median	All	0.668	0.904	<.001	72	view →
READ	OS	Median	II,III,IV	0.919	0.324	.001	37	view →
UCEC	OS	Median	All	0.904	0.947	.002	34	view →
LIHC	DFS	Median	All	0.464	0.610	<.001	32	view →
KIRP	OS	Quartile	II,III,IV	0.173	0.713	.007	24	view →
LGG	DFS	Quartile	All	0.669	0.852	<.001	22	view →
UVM	DFS	Median	III,IV	0.375	0.690	.010	16	view →
UCS	DFS	Median	IV	0.952	0.367	.001	12	view →
PCPG	OS	Median	All	0.625	1.000	.004	12	view →
THCA	DFS	Quartile	III,IV	0.578	0.855	.018	11	view →
MESO	DFS	Median	IV	0.186	0.412	.039	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

GTF3C2-AS1–KIRC (OS)

Open the KIRC breakdown →