Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, GTF2IRD2 mutation is significantly associated with the RNA expression of many other genes, with 1,500 significant associations in total. UCEC shows the largest number of these associations.
The most reproducible GTF2IRD2-associated genes across cancer lineages are DFFA, SEC24C, and RAD51. Each is linked with GTF2IRD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GTF2IRD2-to-partner and partner-to-GTF2IRD2 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (GTF2IRD2→partner) and Y-score (partner→GTF2IRD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.