GTF2IRD1

Across TCGA patient cohorts, GTF2IRD1 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,465 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GTF2IRD1-associated proteins across cancer lineages are PUS7, GPRIN3_S514, and GTF3C4. Each is linked with GTF2IRD1 in more than 6 cancer types. Because this analysis shows association rather than direction, both GTF2IRD1-to-partner and partner-to-GTF2IRD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GTF2IRD1 versus PUS7 in HNSC, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2IRD1→partner) and Y-score (partner→GTF2IRD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PUS7 →	+0.500	+0.694	<.001	<.001	3	7
LSCC	GPRIN3_S514 →	-0.857	-0.826	.001	<.001	3	7
LSCC	GTF3C4 →	+0.310	+0.602	<.001	<.001	3	7
HNSC	GTF2I →	+0.439	+0.620	.001	<.001	3	7
GBM	IL16 →	-0.569	-0.546	<.001	<.001	3	7
HNSC	RASAL3 →	-0.484	-0.885	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,465 associations by consensus.

GTF2IRD1 vs PUS7 — HNSC

Explore this scatter interactively →