GTF2IRD1

Across TCGA patient cohorts, GTF2IRD1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,848 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GTF2IRD1-associated genes across cancer lineages are GTF3C2, ATP6V1FNB, and TIGD5. Each is linked with GTF2IRD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GTF2IRD1-to-partner and partner-to-GTF2IRD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GTF2IRD1 versus GTF3C2 in GBM, with a Pearson correlation of 0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2IRD1→partner) and Y-score (partner→GTF2IRD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GTF3C2 →	+0.599	+0.736	.004	.009	3	3
UCEC	ATP6V1FNB →	+0.621	+0.348	.002	.001	3	3
GBM	TIGD5 →	+0.630	+1.002	.007	.006	3	3
GBM	C8orf82 →	+0.929	+1.002	.006	.006	3	3
OV	CD7 →	-1.324	-0.685	<.001	.003	3	2
UCEC	NEBL-AS1 →	-0.542	-0.291	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,848 associations by consensus.

GTF2IRD1 vs GTF3C2 — GBM

Explore this scatter interactively →