GTF2IRD1

Across TCGA cell cohorts, GTF2IRD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,034 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GTF2IRD1-associated GO terms across cancer lineages are Negative regulation of syncytium formation by plasma membrane fusion, Nucleic acid transport, and RNA transport. Each is linked with GTF2IRD1 in more than 8 cancer types. Because this analysis shows association rather than direction, both GTF2IRD1-to-partner and partner-to-GTF2IRD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of syncytium formation by plasma membrane fusion grouped by GTF2IRD1-low versus GTF2IRD1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2IRD1→partner) and Y-score (partner→GTF2IRD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Negative regulation of syncytium formation by plasma membrane fusion →	+0.092	+1.338	<.001	.006	3	9
BONE	Nucleic acid transport →	+0.108	+1.085	.003	<.001	3	9
BONE	RNA transport →	+0.108	+1.085	.003	<.001	3	9
BLOOD_Lymphoma	Negative regulation of myoblast fusion →	+0.094	+1.338	<.001	.006	3	8
UPPER_AERODIGESTIVE_TRACT	Regulation of syncytium formation by plasma membrane fusion →	+0.087	+0.800	<.001	<.001	2	9
BONE	Positive regulation of double-strand break repair →	+0.078	+1.026	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,034 associations by consensus.

Negative regulation of syncytium formation by plasma membrane fusion by GTF2IRD1 expression — BLOOD_Lymphoma

Explore this box plot interactively →