GTF2IP8

Across TCGA patient cohorts, GTF2IP8 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,237 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GTF2IP8-associated GO terms across cancer lineages are Spindle organization, Telomere maintenance via telomere lengthening, and Microtubule polymerization or depolymerization. Each is linked with GTF2IP8 in more than 8 cancer types. Because this analysis shows association rather than direction, both GTF2IP8-to-partner and partner-to-GTF2IP8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spindle organization grouped by GTF2IP8-low versus GTF2IP8-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2IP8→partner) and Y-score (partner→GTF2IP8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Spindle organization →	+0.126	+0.109	<.001	<.001	3	9
STAD	Telomere maintenance via telomere lengthening →	+0.116	+0.099	<.001	<.001	3	8
STAD	Microtubule polymerization or depolymerization →	+0.103	+0.107	<.001	<.001	3	8
STAD	Protein targeting to vacuole →	+0.112	+0.106	<.001	<.001	3	8
STAD	Respiratory system development →	+0.091	+0.096	<.001	<.001	3	8
STAD	Regulation of binding →	+0.109	+0.103	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,237 associations by consensus.

Spindle organization by GTF2IP8 expression — STAD

Explore this box plot interactively →