GTF2IP22

Across TCGA patient cohorts, GTF2IP22 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,245 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GTF2IP22-associated GO terms across cancer lineages are Protein acetylation, Methylation, and Phospholipid biosynthetic process. Each is linked with GTF2IP22 in more than 8 cancer types. Because this analysis shows association rather than direction, both GTF2IP22-to-partner and partner-to-GTF2IP22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein acetylation grouped by GTF2IP22-low versus GTF2IP22-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2IP22→partner) and Y-score (partner→GTF2IP22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Protein acetylation →	+0.114	+0.253	<.001	.002	3	9
STAD	Methylation →	+0.108	+0.246	<.001	<.001	3	8
STAD	Phospholipid biosynthetic process →	+0.112	+0.187	<.001	<.001	3	8
STAD	Response to monosaccharide →	+0.075	+0.221	<.001	<.001	3	8
ESCA	Macromolecule methylation →	+0.113	+0.275	<.001	.002	3	8
STAD	Regulation of ubiquitin-dependent protein catabolic process →	+0.124	+0.194	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,245 associations by consensus.

Protein acetylation by GTF2IP22 expression — ESCA

Explore this box plot interactively →