GTF2H5

Across TCGA pan-cancer cohorts, GTF2H5 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated GTF2H5 data layer compared with 25 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher GTF2H5 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated GTF2H5 expression acts as an unfavorable survival marker, although some lineages such as LUAD and CCRCC show a favorable association.

HNSC, PDAC, and LUAD are the cancer types where GTF2H5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	All	0.121	1.000	.017	40	view →
PDAC	OS	Median	All	0.275	0.434	.012	14	view →
LUAD	DFS	Quartile	All	0.999	0.836	.006	9	view →
CCRCC	OS	Median	IV	1.000	0.150	.036	4	view →
LSCC	DFS	Median	III,IV	0.882	1.000	.039	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

GTF2H5–HNSC (OS)

Open the HNSC breakdown →