GTF2H3

Across TCGA patient cohorts, GTF2H3 protein abundance is significantly associated with the RNA expression of many other genes, with 8,953 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GTF2H3-associated genes across cancer lineages are PRMT3, SNRPC, and C11orf58. Each is linked with GTF2H3 in more than 3 cancer types. Because this analysis shows association rather than direction, both GTF2H3-to-partner and partner-to-GTF2H3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GTF2H3 versus PRMT3 in HNSC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2H3→partner) and Y-score (partner→GTF2H3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PRMT3 →	+0.796	+0.223	<.001	<.001	3	4
HNSC	SNRPC →	+0.829	+0.193	.006	.002	3	4
HNSC	C11orf58 →	+0.618	+0.194	.002	.001	3	3
OV	GTF2H1 →	+0.912	+0.437	<.001	<.001	3	3
LSCC	CSE1L →	+0.665	+0.246	<.001	<.001	3	3
HNSC	BTBD10 →	+0.792	+0.231	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,953 associations by consensus.

GTF2H3 vs PRMT3 — HNSC

Explore this scatter interactively →