Across TCGA patient cohorts, GTF2H2B mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GTF2H2B-associated genes across cancer lineages are IQCF2, MIR1225, and RNU2-50P. Each is linked with GTF2H2B in more than 1 cancer types. Because this analysis shows association rather than direction, both GTF2H2B-to-partner and partner-to-GTF2H2B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2H2B→partner) and Y-score (partner→GTF2H2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IQCF2 →	+0.420	+4.211	<.001	.009	3	1
UCEC	MIR1225 →	+0.886	+5.027	<.001	.004	3	1
UCEC	RNU2-50P →	+0.571	+4.423	.007	.006	3	1
UCEC	RNA5SP369 →	+1.168	+4.778	<.001	.003	3	1
UCEC	RPS12P10 →	+0.391	+4.211	.001	.009	3	1
UCEC	MTATP6P21 →	+0.605	+4.552	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

GTF2H2B survival (RNA) · tumor vs normal (RNA) · all GTF2H2B data types