Across TCGA patient cohorts, GTF2H2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,698 significant associations in total. LIHC shows the largest number of these associations.

The most reproducible GTF2H2-associated GO terms across cancer lineages are Regulation of DNA duplex unwinding, Positive regulation of rRNA processing, and Transcription by RNA polymerase III. Each is linked with GTF2H2 in more than 26 cancer types. Because this analysis shows association rather than direction, both GTF2H2-to-partner and partner-to-GTF2H2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2H2→partner) and Y-score (partner→GTF2H2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of DNA duplex unwinding →	-0.056	-0.445	<.001	<.001	3	27
ACC	Positive regulation of rRNA processing →	+0.051	+0.856	<.001	<.001	3	26
UVM	Transcription by RNA polymerase III →	+0.045	+0.565	<.001	<.001	3	26
UVM	Maturation of SSU-rRNA →	+0.050	+0.523	<.001	<.001	3	25
SCLC	Error-prone translesion synthesis →	+0.090	+0.776	.001	.001	2	26
UVM	Double-strand break repair via nonhomologous end joining →	+0.035	+0.513	<.001	<.001	3	25

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,698 associations by consensus.

Exploration

GTF2H2 survival (RNA) · tumor vs normal (RNA) · all GTF2H2 data types