GTF2H2

Across TCGA cell cohorts, GTF2H2 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GTF2H2-associated genes across cancer lineages are GUCA1C. Each is linked with GTF2H2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GTF2H2-to-partner and partner-to-GTF2H2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GUCA1C grouped by GTF2H2-low versus GTF2H2-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2H2→partner) and Y-score (partner→GTF2H2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	GUCA1C →	+0.032	+5.969	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

GUCA1C by GTF2H2 expression — BLOOD_Leukemia

Explore this box plot interactively →